Crystal Mackall, MD: Unleashing the Hounds

Year Funded: 2015

Crystal Mackall: Unleashing the Hounds

“To use a patient’s own immune system to fight cancer, we need to turn that patient’s CAR T cells into bloodhounds. We train them to sniff out and kill cancer cells,” says Crystal Mackall, MD, of Stanford University (Stanford,

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Noriyuki Kasahara, MD, PhD: Finding a Better Way

Year Funded: 2017

Noriyuki Kasahara, MD, PhD: Finding a Better Way

When Noriyuki Kasahara, MD, PhD, was a student in medical school, he watched his aunt lay in a coma for nearly a year, dying of glioblastoma. It was then that he realized that, as a physician,

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Brent Hanks, MD, PhD: Feeling optimistic

Year Funded: 2015

BRENT HANKS: I Feel Optimistic

Melanoma has been steadily increasing in recent years, and despite improvements in diagnosis and early stage treatment, metastatic cancer patients face staggering low chances for recovery. At Duke University School of Medicine (Durham, N.C.), tumor immunologist Brent Hanks,

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Joseph Glorioso, III: Turning Bad Guys into Good Guys

Year Funded: 2018

Joseph Glorioso, III: Turning Bad Guys into Good Guys

“I was originally trained as a virologist,” says Joseph Glorioso, III, MD, PhD, of the University of Pittsburgh School of Medicine Department of Microbiology and Molecular Genetics (Pittsburgh, Pa.).
Viruses naturally cause disease,

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Dr. Seth Pollack: Knocking down Barriers

Year Funded: 2017

Dr. Seth Pollack: We Just Need to Keep Knocking

NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is an antigen that is associated with many cancers, but is expressed with particular vigor in synovial sarcomas and myxoid/round cell liposarcoma. Both of these sarcomas typically occur in about 1,000 young Americans every year.

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