Joseph Glorioso, III: Turning Bad Guys into Good Guys

Year Funded: 2018

Joseph Glorioso, III: Turning Bad Guys into Good Guys

“I was originally trained as a virologist,” says Joseph Glorioso, III, MD, PhD, of the University of Pittsburgh School of Medicine Department of Microbiology and Molecular Genetics (Pittsburgh, Pa.).
Viruses naturally cause disease,

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Dr. Seth Pollack: Knocking down Barriers

Year Funded: 2017

Dr. Seth Pollack: We Just Need to Keep Knocking

NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is an antigen that is associated with many cancers, but is expressed with particular vigor in synovial sarcomas and myxoid/round cell liposarcoma. Both of these sarcomas typically occur in about 1,000 young Americans every year.

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Dr. Daniel J. Powell: An Optimistic Doctor

Year Funded: 2017

Dr. Daniel J. Powell: An Optimistic Doctor

For women battling advanced ovarian cancer who have completed at least two rounds of chemotherapy without results, Daniel J. Powell, Jr., PhD, and colleagues at the University of Pennsylvania Perelman School of Medicine (Philadelphia, Pa.) are offering new hope.

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Dr. Miguel Sena Esteves: Delivering Gene Therapy

Year Funded: 2005

Dr. Miguel Sena-Esteves: Taking an Engineering Approach to Biology

“I have no doubt that gene therapy is the path to a future of precision medicine,” says Miguel Sena-Esteves, PhD, of the University of Massachusetts Medical School (Worcester, Mass.). “Recent clinical trials show this unequivocally,

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Dr. Khalid Shah: Treating Brain Tumors – How can we approach this differently?

Year Funded: 2007

Dr. Khalid Shah: How can we approach this differently?

“Malignant glioblastomas have virtually defied all therapeutic modalities to date,” says Khalid Shah, MS, PhD, director of the Center for Stem Cell Therapeutics and Imaging and vice chair of the Department of Neurosurgery Research at Brigham and Women’s Hospital (Boston,

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