Herbert Zeh, III MD, FACS

UT Southwestern Medical Center, Dallas, TX Hall and Mary Lucile Shannon Distinguished Chair in Surgery, Professor and Chair of the Department of Surgery

Research Focus: Immunotherapy

Cancer Type: Pancreatic Cancer

Award: Clinical Investigator

Dr. Zeh’s expertise lies in cancers and diseases of the pancreas and the use of state-of-the-art robotic technology. This award will allow Dr. Zeh and his team to continue focusing on immunotherapy techniques using viruses to stimulate the immune system to fight pancreatic cancer.

“I am honored to receive this generous award from ACGT. Studies utilizing gene therapy as a treatment technique for pancreatic cancer have shown great promise to date. It is my hope that my research will bring the medical community one step closer to beating pancreatic cancer,” said Dr. Zeh.

His proposal utilizes a gene therapy approach that has proven extremely successful in the laboratory. In these newly-funded studies, Dr. Zeh’s team will use a modified virus to produce hormones that attract a tumor-fighting T cell that not only kills cancer but also protects the patient against potential recurrence. This approach, also used to treat patients with brain tumors, has proven toxic to cancer cells and also holds greater potential for long-term survival.

Prior to joining UT Southwestern, Dr. Zeh was chief of the Division of Gastrointestinal (GI) Surgical Oncology at UPMC Cancer Center and Co-Directed the UPMC Pancreatic Cancer Center. Dr. Zeh received his bachelor’s degree from the University of Notre Dame and his medical degree from the University of Pittsburgh School of Medicine.

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