Roberto Cattaneo, PhD

Roberto Cattaneo, PhD
Mayo Clinic College of Medicine (Rochester, MN)
 

Year Funded:
2006

Focus:
Leukemia / Lymphoma

Tumor specific replicating virus.

Studies in recent years have documented the lytic effects of various viruses on many human cancers, and the study and re-engineering of oncolytic viruses is intensifying. Recombinant measles viruses [MV] appear to be ideal vectors for lymphoma treatment, as wild-type MV infection occasionally induces lymphoma regression in humans.  

We plan to produce viruses that replicate selectively in transformed lymphocytes, viruses with modulatable cytotoxicity, and viruses with a targeted envelope. Eventually we will combine the characteristics of the most effective viruses into a ‘second generation’ virus that is armed and targeted.

Academic Profile

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Robert Cattaneo, PhD
Professor of Biochemistry and Molecular Biology
Mayo Clinic
200 First St. SW
Rochester, MN 55905