Timothy Lane, PhD

Timothy Lane, PhD
Jonsson Comprehensive Cancer Center, University of California, Los Angeles (Los Angeles, CA)
 

Year Funded:
2003

Focus:
Breast Cancer

Anti-angiogenesis: seeking a new target for cancer treatment.

Since most human tumors must recruit new blood vessels in order to grow and move, anti-angiogenic therapies have been viewed as a potential complement to more traditional cancer treatments. We have identified a genetic element that allows genes to be expressed in a group of bone marrow derived cells that contribute to cancer-associated blood vessels.  

The cells are called “endothelial cell precursors” (ECPs). ECPs are a special type of stem cell that play a role in the formation of new blood vessels. We propose to create a simple virus designed to carry genes to ECPs and prevent them from helping tumors to grow. 

Academic Profile

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Timothy Lane, PhD
Professor of Medical Education and of Biochemistry and Molecular Genetics
Northwestern University
Feinberg School of Medicine
420 E. Superior St.
Chicago, IL 60611