…Biospace. Retrieved from: https://www.biospace.com/article/releases/genprex-announces-first-patient-dosed-in-phase-1-2-acclaim-1-clinical-trial-of-reqorsa-immunogene-therapy-in-combination-with-tagrisso-to-treat-non-small-cell-lung-cancer/. Accessed: 03/04/2022. Our Science. A2 Bio. Retrieved from: https://www.a2bio.com/science/. Accessed: 03/04/2022. A2 Bio Publishes Key Preclinical Findings Demonstrating Potential of Its Highly Selective Tmod™ Cell Therapy…
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…Retrieved from: https://www.medscape.com/viewarticle/964646. Accessed: 12/13/2021. Treatment With Cilta-Cel Continues Yield Robust, Long-Lasting Outcomes in Relapsed/Refractory Multiple Myeloma. Cancer Network. Retrieved from: https://www.cancernetwork.com/view/treatment-with-cilta-cel-continues-yield-robust-long-lasting-outcomes-in-relapsed-refractory-multiple-myeloma. Accessed: 12/14/2021 Mustang Bio Announces Updated Interim Phase…
…Corporate Update. Biospace. Retrieved from: https://www.biospace.com/article/releases/tcr-therapeutics-reports-first-quarter-2022-financial-results-and-provides-corporate-update/. Accessed: 05/13/2022. Is mesothelin a key to tackling solid tumors? Some biotech companies are betting that it is. STATnews. Retrieved from: https://www.statnews.com/2023/01/20/mesothelin-solid-tumors-cancer-biotech-companies/. Accessed: 01/23/2023….
…Food and Drug Administration. Retrieved from: https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-lifileucel-unresectable-or-metastatic-melanoma. Accessed: 02/20/2024. FDA approves first tumour-infiltrating lymphocyte (TIL) therapy, bolstering hopes for cell therapies in solid cancers. Nature. Retrieved from: https://www.nature.com/articles/d41573-024-00035-1. Accessed: 02/20/2024….
…eradication. Presently, we are the only group in the world with the combined expertise to test this hypothesis. In this proposal we will: (1) Generate and test in vitro human…
…complimentary of each individual company. “By combining Carisma’s expertise in engineered macrophage biology and Moderna’s pioneering in vivo mRNA delivery technologies, we are excited about the potential of this novel…
…01/19/2022. How Does CAR T-Cell Therapy Work in Treating Cancer? American Society of Clinical Oncology. Retrieved from: https://www.cancer.net/blog/2021-06/how-does-car-t-cell-therapy-work-treating-cancer. Accessed: 01/19/2022. Frequently asked questions. Mayo Clinic. Retrieved from: https://www.mayoclinic.org/departments-centers/car-t-cell-therapy-program/sections/gnc-20405547. Accessed: 01/19/2022….
…https://www.nbcnews.com/health/health-news/gene-therapy-pancreatic-cancer-experimental-approach-shrank-tumors-one-rcna31437. Accessed: 06/03/2022. Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer. New England Journal of Medicine. Retrieved from: https://www.nejm.org/doi/full/10.1056/NEJMoa2119662. Accessed: 06/03/2022. Reprogrammed Cells Attack and Tame Deadly Cancer in One…
…T cells. Abstracts Online. Retrieved from: https://www.abstractsonline.com/pp8/#!/10517/presentation/20143. Accessed: 04/12/2022. Revolutionary leukemia treatment offers ‘a hopeful moment’ in fight against solid tumors. USA Today. Retrieved from: https://www.usatoday.com/story/news/health/2022/04/10/cancer-treatment-car-t-immunotherapy/9513108002/. Accessed: 04/12/2022. Childhood Diffuse…
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…migrating to the tumor – much more than with other therapies. We think this is a way to stimulate the immune system to begin attacking the tumor.” https://www.youtube.com/watch?v=qs5ec251jq0 ACGT-funded research…
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…for DMGs in the clinic. With this proposal, we will test the benefit of a specific immunotherapy approach referred to as adoptive T-cell transfer, which gives the patient a large…
…into solid tumors, glioblastoma emerges as area of opportunity. Healio. Retrieved from: https://www.healio.com/news/hematology-oncology/20211111/as-cart-advances-into-solid-tumors-glioblastoma-emerges-as-area-of-opportunity. Accessed: 11/15/2021. Mustang Bio Announces MB-101 (IL13Rα2βtargeted CAR T cells) Scientific Presentations at Upcoming Virtual Conferences. Mustang…
…Cilta-cel to Treat R/R Multiple Myeloma. American Journal of Managed Care. Retrieved from: https://www.ajmc.com/view/fda-approves-cilta-cel-to-treat-r-r-multiple-myeloma. Accessed: 03/01/2022. U.S. FDA Approves CARVYKTI™ (ciltacabtagene autoleucel), Janssen’s First Cell Therapy, a BCMA-Directed CAR-T Immunotherapy…
…New Phase. American Journal of Managed Care. Retrieved from: https://www.ajmc.com/view/with-approval-for-axi-cel-in-second-line-on-the-horizon-car-t-cell-therapy-poised-to-enter-new-phase. Accessed: 02/16/2022. FDA Agrees to Review CAR-T Cell Therapy for Second-Line Treatment of Large B-Cell Lymphoma. CURE. Retrieved from: https://www.curetoday.com/view/fda-agrees-to-review-car-t-cell-therapy-for-second-line-treatment-of-large-b-cell-lymphoma….
…therapies for several types of blood cancer. The latest FDA approval stems from Yescarta’s success in the recent ZUMA-7 clinical trial. The phase 3 study tested the CAR T-cell therapy…
…ZUMA-7 clinical trial leads to approval The results of the ZUMA-7 clinical trial spearheaded the new FDA approval. The study included 359 patients and 77 cancer institutions. Patients were slotted…
https://www.youtube.com/watch?v=7N5CGRS0SbU The collaboration is based on the incredible progress of cell and gene therapies in other cancers and our mission to bring this same success to the most difficult to…