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Explaining how T-cell receptors can treat cancer

…T cells. HLA is part of the major histocompatibility complex (MHC), which includes fragments of proteins called peptides. When these peptides are from a cancerous protein, HLA presents them to…

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Lotze Lifetime Acheivement

…on gene therapy protocols at the University of Pittsburgh. He is the co-inventor of 10 patents in dendritic cell vaccines and antigen discovery, and author of more than 500 scientific…

How does memory of T cells impact CAR T-cell therapy?

…cells’ specific characteristics – such as protein antigens serving as fingerprint identification – are crucial. These cells react quickly and with force when they come into contact with other cancer…

Barbara Lavery

…Ms. Lavery is responsible for programmatic initiatives, including leadership of the Academic Research Program and the Biotechnology Investment Program. “This is my dream job,” says Ms. Lavery. “It combines science…

Kevin Honeycutt

Kevin Honeycutt was named CEO and president of Alliance for Cancer Gene Therapy in December 2018 and elected to its board of directors in June 2022. As chief executive officer,…

Chen Y

…been hailed as one of the most promising breakthroughs in cancer therapy, and its full potential beyond the treatment of B-cell malignancies remains to be realized. Successful completion of the…

Bartlett

…diseases as well.  Ovarian cancer is one of the most common and frequently life-threatening malignancies affecting women in the U.S. today: about 25,000 new cases will be diagnosed with the…

Levitsky

…GM-CSF tumor vaccines in a mouse model (year 1).   2. Conduct a clinical trial in MDS testing K562/GM-CSF vaccination integrated with the systemic agent(s) identified in aim 1 as…