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…diseases in humans. This study will test the hypothesis that SV5 mutant viruses can selectively kill advanced tumors. SV5 viruses with mutation in SH or V proteins induce apoptosis in…

Jain

Anti-angiogenesis is a way of strangulating the blood supply of a tumor, since without new blood, the tumor cannot survive. Dr. Jain’s study will test an alternative treatment using a…

Tribute Test

Lin

…virus that enhance its ability to replicate in cells have shown further improvements in tumor killing in preclinical testing. As this therapeutic virus platform is modified to be more lethal…

Sauthoff

…efficient distribution within tumors, compared to complexly folded large proteins. The delivery of peptides fused to a protein transduction domain with adenoviral vectors is a new approach that could find…

Yang Y

…to activate both cDCs and pDCs and to produce pro-inflammatory cytokines and type I IFNs, respectively. In addition, CpG can also activate NK cells. In this application, we will test…

Bell

When John Bell, PhD, and his team of bright, young scholars from around the globe go to work at the Ottawa Hospital Cancer Centre (Ottawa, ON, Canada), they come face-to-face…

Hegde

“Solid tumors are complex and highly heterogenous,” says Meenakshi Hegde, MD, a pediatric oncologist who conducts translational immunotherapy research at the Baylor College of Medicine Center for Cell and Gene…

Chen Y

…at the molecular level. With a grant from Alliance for Cancer Gene Therapy, Dr. Chen began to organize an ambitious high-throughput screening (HTS) initiative to test thousands of CAR variants…

National Cancer Research Month: 5 ACGT-funded research projects

…to advance cancer research. Funding from the Alliance has led to clinical trials, the first FDA-approved cell and gene therapies for cancer, and more patients living cancer-free for more than…

Overview of the International Oncolytic Virotherapy Conference

…explore international collaborations while enabling pharmaceutical companies to access the cutting-edge research happening in small biotech and academic labs, in an atmosphere where the free exchange of scientific knowledge is…

Donor-advised funds

…from your account while the balance is allowed to appreciate tax-free. There are hundreds of DAF options in the market today. For example, Fidelity Charitable, Jewish Communal Fund and JP…

Contact Thank You

Thank you for connecting with us! You are officially part of ACGT’s alliance working toward a cancer-free future. Stay tuned for our tailored monthly e-communications. In the meantime, please check…

Contact Thank You

Keri Eisenberg

…fundraising initiatives and fostering philanthropic alliances with individual donors, corporations, medical institutions, nonprofit partner organizations and other stakeholders committed to advancing cell and gene therapy for cancer. “My role is…

Should the CAR T-cell therapy Abecma be available sooner to multiple myeloma patients?

…point when Abecma becomes an option. A new study tested using Abecma earlier in the treatment process – with promising results. Bristol Myers Squibb (BMS) announced interim results of the…

Celebrating the 5-year anniversary of Kymriah’s FDA approval

As the cliche goes, “All it takes is one.” Once the first one comes, many more follow. This statement is poignant when talking about the emergence of CAR T-cell therapy…

Cancer cell and gene therapy in 2022: What’s ACGT planning

…for blood cancers, including types of lymphoma, myeloma, and leukemia. Clinical trials using next-generation CAR T cells and other cell and gene therapies – and combining them with immunotherapies and…

Sharon DaCosta

…Cancer Gene Therapy, including but not limited to management of the donor database, prepare donor communications, oversight of grant requests and payment timelines, assistance with external communication efforts, such as…

Griffith

…United States. We are studying and testing a new means of inhibiting the formation of prostate tumors, using an agent called TRAIL to induce the death of tumor cells. The…